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GSK3β is a negative regulator of platelet function and thrombosis

Glycogen synthase kinase (GSK)3β is a ser-thr kinase that is phosphorylated by the kinase Akt. Although Akt has been shown to regulate platelet function and arterial thrombosis, its effectors in platelets remain unknown. We show here that agonist-dependent phosphorylation of GSK3β in platelets is Ak...

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Detalhes bibliográficos
Main Authors: Li, Dongjun, August, Shelley, Woulfe, Donna S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2275019/
https://ncbi.nlm.nih.gov/pubmed/18218855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-09-111518
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