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GSK3β is a negative regulator of platelet function and thrombosis

Glycogen synthase kinase (GSK)3β is a ser-thr kinase that is phosphorylated by the kinase Akt. Although Akt has been shown to regulate platelet function and arterial thrombosis, its effectors in platelets remain unknown. We show here that agonist-dependent phosphorylation of GSK3β in platelets is Ak...

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Autori principali: Li, Dongjun, August, Shelley, Woulfe, Donna S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2275019/
https://ncbi.nlm.nih.gov/pubmed/18218855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-09-111518
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