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GSK3β is a negative regulator of platelet function and thrombosis

Glycogen synthase kinase (GSK)3β is a ser-thr kinase that is phosphorylated by the kinase Akt. Although Akt has been shown to regulate platelet function and arterial thrombosis, its effectors in platelets remain unknown. We show here that agonist-dependent phosphorylation of GSK3β in platelets is Ak...

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Autors principals: Li, Dongjun, August, Shelley, Woulfe, Donna S.
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2275019/
https://ncbi.nlm.nih.gov/pubmed/18218855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-09-111518
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