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Amino Acid Mutation N348I in the Connection Subdomain of Human Immunodeficiency Virus Type 1 Reverse Transcriptase Confers Multiclass Resistance to Nucleoside and Nonnucleoside Reverse Transcriptase Inhibitors
We identified clinical isolates with phenotypic resistance to nevirapine (NVP) in the absence of known nonnucleoside reverse transcriptase inhibitor (NNRTI) mutations. This resistance is caused by N348I, a mutation at the connection subdomain of human immunodeficiency virus type 1 (HIV-1) reverse tr...
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Główni autorzy: | , , , , , , , , |
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Format: | Artigo |
Język: | Inglês |
Wydane: |
American Society for Microbiology (ASM)
2008
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Hasła przedmiotowe: | |
Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2268505/ https://ncbi.nlm.nih.gov/pubmed/18216099 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01154-07 |
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