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Nonnucleoside reverse transcriptase inhibitors are chemical enhancers of dimerization of the HIV type 1 reverse transcriptase

Nonnucleoside reverse transcriptase inhibitors (NNRTIs) are allosteric inhibitors of the HIV type 1 (HIV-1) reverse transcriptase (RT). Yeast grown in the presence of many of these drugs exhibited dramatically increased association of the p66 and p51 subunits of the HIV-1 RT as reported by a yeast t...

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Bibliografiske detaljer
Main Authors: Tachedjian, Gilda, Orlova, Marianna, Sarafianos, Stefan G., Arnold, Edward, Goff, Stephen P.
Format: Artigo
Sprog:Inglês
Udgivet: The National Academy of Sciences 2001
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC34644/
https://ncbi.nlm.nih.gov/pubmed/11416202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.121055998
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