Nonnucleoside reverse transcriptase inhibitors that potently and specifically block human immunodeficiency virus type 1 replication.

Certain bis(heteroaryl)piperazines (BHAPs) are potent inhibitors of the human immunodeficiency virus type 1 (HIV-1) reverse transcriptase (RT) at concentrations lower by 2-4 orders of magnitude than that which inhibits normal cellular DNA polymerase activity. Combination of a BHAP with nucleoside an...

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Detalhes bibliográficos
Main Authors: Romero, D L, Busso, M, Tan, C K, Reusser, F, Palmer, J R, Poppe, S M, Aristoff, P A, Downey, K M, So, A G, Resnick, L
Formato: Artigo
Idioma:Inglês
Publicado em: 1991
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC52599/
https://ncbi.nlm.nih.gov/pubmed/1717988
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