Structure of the binding site for nonnucleoside inhibitors of the reverse transcriptase of human immunodeficiency virus type 1.

The dipyridodiazepinone Nevirapine is a potent and highly specific inhibitor of the reverse transcriptase (RT) from human immunodeficiency virus type 1 (HIV-1). It is a member of an important class of nonnucleoside drugs that appear to share part or all of the same binding site on the enzyme but are...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Smerdon, S J, Jäger, J, Wang, J, Kohlstaedt, L A, Chirino, A J, Friedman, J M, Rice, P A, Steitz, T A
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1994
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC43692/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7513427/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.9.3911
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