Nonnucleoside reverse transcriptase inhibitors that potently and specifically block human immunodeficiency virus type 1 replication.

Certain bis(heteroaryl)piperazines (BHAPs) are potent inhibitors of the human immunodeficiency virus type 1 (HIV-1) reverse transcriptase (RT) at concentrations lower by 2-4 orders of magnitude than that which inhibits normal cellular DNA polymerase activity. Combination of a BHAP with nucleoside an...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Romero, D L, Busso, M, Tan, C K, Reusser, F, Palmer, J R, Poppe, S M, Aristoff, P A, Downey, K M, So, A G, Resnick, L
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1991
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC52599/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1717988/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.19.8806
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