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Structural Analysis of Actinorhodin Polyketide Ketoreductase: Cofactor Binding and Substrate Specificity

Aromatic polyketides are a class of natural products that include many pharmaceutically important aromatic compounds. Understanding the structure and function of PKS will provide clues to the molecular basis of polyketide biosynthesis specificity. Polyketide chain reduction by ketoreductase (KR) pro...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Korman, Tyler Paz, Hill, Jason Anthony, Vu, Thanh Nhat, Tsai, Shiou-Chuan
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2004
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2263080/
https://ncbi.nlm.nih.gov/pubmed/15544323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi048133a
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