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Structural Analysis of Actinorhodin Polyketide Ketoreductase: Cofactor Binding and Substrate Specificity

Aromatic polyketides are a class of natural products that include many pharmaceutically important aromatic compounds. Understanding the structure and function of PKS will provide clues to the molecular basis of polyketide biosynthesis specificity. Polyketide chain reduction by ketoreductase (KR) pro...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Korman, Tyler Paz, Hill, Jason Anthony, Vu, Thanh Nhat, Tsai, Shiou-Chuan
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2004
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2263080/
https://ncbi.nlm.nih.gov/pubmed/15544323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi048133a
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