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Inhibition Kinetics and Emodin Cocrystal Structure of a Type II Polyketide Ketoreductase,
Type II polyketides are a class of natural products that include pharmaceutically important aromatic compounds such as the antibiotic tetracycline and antitumor compound doxorubicin. The type II polyketide synthase (PKS) is a complex consisting of 5–10 standalone domains homologous to fatty acid syn...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2263082/ https://ncbi.nlm.nih.gov/pubmed/18205400 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi7016427 |
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