Structural consequences of the familial amyotrophic lateral sclerosis SOD1 mutant His46Arg

The His46Arg (H46R) mutant of human copper-zinc superoxide dismutase (SOD1) is associated with an unusual, slowly progressing form of familial amyotrophic lateral sclerosis (FALS). Here we describe in detail the crystal structures of pathogenic H46R SOD1 in the Zn-loaded (Zn-H46R) and metal-free (ap...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Antonyuk, Svetlana, Elam, Jennifer Stine, Hough, Michael A., Strange, Richard W., Doucette, Peter A., Rodriguez, Jorge A., Hayward, Lawrence J., Valentine, Joan Selverstone, Hart, P. John, Hasnain, S. Samar
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Cold Spring Harbor Laboratory Press 2005
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2253262/
https://ncbi.nlm.nih.gov/pubmed/15840828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.041256705
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg