Structures of the G85R Variant of SOD1 in Familial Amyotrophic Lateral Sclerosis

Mutations in the gene encoding human copper-zinc superoxide dismutase (SOD1) cause a dominant form of the progressive neurodegenerative disease amyotrophic lateral sclerosis. Transgenic mice expressing the human G85R SOD1 variant develop paralytic symptoms concomitant with the appearance of SOD1-enr...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Cao, Xiaohang, Antonyuk, Svetlana V., Seetharaman, Sai V., Whitson, Lisa J., Taylor, Alexander B., Holloway, Stephen P., Strange, Richard W., Doucette, Peter A., Valentine, Joan Selverstone, Tiwari, Ashutosh, Hayward, Lawrence J., Padua, Shelby, Cohlberg, Jeffrey A., Hasnain, S. Samar, Hart, P. John
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Biochemistry and Molecular Biology 2008
Aiheet:
Protein Structure and Folding
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2414278/
https://ncbi.nlm.nih.gov/pubmed/18378676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M801522200
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