E47 is required for V(D)J recombinase activity in common lymphoid progenitors

Common lymphoid progenitors (CLPs) are the first bone marrow precursors in which V(D)J recombinase activity is up-regulated. Here, we show that loss of the transcription factor E47 produces a reduced CLP population that lacks V(D)J recombinase activity and D-J(H) rearrangements in vivo. Apart from a...

全面介紹

Na minha lista:
書目詳細資料
Main Authors: Borghesi, Lisa, Aites, Jennifer, Nelson, Shakira, Lefterov, Preslav, James, Pamela, Gerstein, Rachel
格式: Artigo
語言:Inglês
出版: The Rockefeller University Press 2005
主題:
Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2212960/
https://ncbi.nlm.nih.gov/pubmed/16365147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20051190
標簽: 添加標簽
沒有標簽, 成為第一個標記此記錄!

相似書籍