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B Lineage–specific Regulation of V(D)J Recombinase Activity Is Established in Common Lymphoid Progenitors

Expression of V(D)J recombinase activity in developing lymphocytes is absolutely required for initiation of V(D)J recombination at antigen receptor loci. However, little is known about when during hematopoietic development the V(D)J recombinase is first active, nor is it known what elements activate...

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Detalhes bibliográficos
Main Authors: Borghesi, Lisa, Hsu, Lih-Yun, Miller, Juli P., Anderson, Michael, Herzenberg, Leonard, Herzenberg, Leonore, Schlissel, Mark S., Allman, David, Gerstein, Rachel M.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2211824/
https://ncbi.nlm.nih.gov/pubmed/14769852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20031800
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