The Earliest Step in B Lineage Differentiation from Common Lymphoid Progenitors Is Critically Dependent upon Interleukin 7

Little is known about the signals that promote early B lineage differentiation from common lymphoid progenitors (CLPs). Using a stromal-free culture system, we show that interleukin (IL)-7 is sufficient to promote the in vitro differentiation of CLPs into B220(+) CD19(+) B lineage progenitors. Consi...

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Autors principals: Miller, Juli P., Izon, David, DeMuth, William, Gerstein, Rachel, Bhandoola, Avinash, Allman, David
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2002
Matèries:
Brief Definitive Report
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193997/
https://ncbi.nlm.nih.gov/pubmed/12208884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20020784
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