The Earliest Step in B Lineage Differentiation from Common Lymphoid Progenitors Is Critically Dependent upon Interleukin 7

Little is known about the signals that promote early B lineage differentiation from common lymphoid progenitors (CLPs). Using a stromal-free culture system, we show that interleukin (IL)-7 is sufficient to promote the in vitro differentiation of CLPs into B220(+) CD19(+) B lineage progenitors. Consi...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Miller, Juli P., Izon, David, DeMuth, William, Gerstein, Rachel, Bhandoola, Avinash, Allman, David
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The Rockefeller University Press 2002
Pynciau:
Brief Definitive Report
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193997/
https://ncbi.nlm.nih.gov/pubmed/12208884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20020784
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