Fli-1 regulates the DN2 to DN3 thymocyte transition and promotes γδ T-cell commitment by enhancing TCR signal strength

Por Smeets, Monique F.M.A, Wiest, David L., Izon, David J.
Publicado no Eur J Immunol (2014)

The Earliest Step in B Lineage Differentiation from Common Lymphoid Progenitors Is Critically Dependent upon Interleukin 7

Por Miller, Juli P., Izon, David, DeMuth, William, Gerstein, Rachel, Bhandoola, Avinash, Allman, David
Publicado em 2002

Fli-1 Overexpression in Hematopoietic Progenitors Deregulates T Cell Development and Induces Pre-T Cell Lymphoblastic Leukaemia/Lymphoma

Por Smeets, Monique F. M. A., Chan, Angela C., Dagger, Samantha, Bradley, Cara K., Wei, Andrew, Izon, David J.
Publicado em 2013

The Zinc-finger protein ASCIZ regulates B cell development via DYNLL1 and Bim

Por Jurado, Sabine, Gleeson, Kimberly, O’Donnell, Kristy, Izon, David J., Walkley, Carl R., Strasser, Andreas, Tarlinton, David M., Heierhorst, Jörg
Publicado em 2012

Identification of Flt3(+)CD150(−) myeloid progenitors in adult mouse bone marrow that harbor T lymphoid developmental potential

Por Chi, Anthony W. S., Chavez, Alejandro, Xu, Lanwei, Weber, Brittany N., Shestova, Olga, Schaffer, Andras, Wertheim, Gerald, Pear, Warren S., Izon, David, Bhandoola, Avinash
Publicado em 2011

ATM Substrate Chk2-interacting Zn(2+) Finger (ASCIZ) Is a Bi-functional Transcriptional Activator and Feedback Sensor in the Regulation of Dynein Light Chain (DYNLL1) Expression

Por Jurado, Sabine, Conlan, Lindus A., Baker, Emma K., Ng, Jane-Lee, Tenis, Nora, Hoch, Nicolas C., Gleeson, Kimberly, Smeets, Monique, Izon, David, Heierhorst, Jörg
Publicado em 2012

Complete Diabetes Protection Despite Delayed Thymic Tolerance in NOD8.3 TCR Transgenic Mice Due to Antigen-Induced Extrathymic Deletion of T Cells

Por Krishnamurthy, Balasubramanian, Chee, Jonathan, Jhala, Gaurang, Fynch, Stacey, Graham, Kate L., Santamaria, Pere, Morahan, Grant, Allison, Janette, Izon, David, Thomas, Helen E., Kay, Thomas W.H.
Publicado em 2012

Perturbed thymopoiesis in vitro in the absence of Suppressor of Cytokine Signalling 1 and 3

Por Croom, Hayley A., Izon, David J., Chong, Mark M., Curtis, David J., Roberts, Andrew W., Kay, Thomas W.H., Hilton, Douglas J., Alexander, Warren S., Starr, Robyn
Publicado no Mol Immunol (2008)

The Rothmund-Thomson syndrome helicase RECQL4 is essential for hematopoiesis

Por Smeets, Monique F., DeLuca, Elisabetta, Wall, Meaghan, Quach, Julie M., Chalk, Alistair M., Deans, Andrew J., Heierhorst, Jörg, Purton, Louise E., Izon, David J., Walkley, Carl R.
Publicado em 2014

Enforced expression of the homeobox gene Mixl1 impairs hematopoietic differentiation and results in acute myeloid leukemia

Por Glaser, Stefan, Metcalf, Donald, Wu, Li, Hart, Adam H., DiRago, Ladina, Mifsud, Sandra, D'Amico, Angela, Dagger, Samantha, Campo, Chiara, Chan, Angela C., Izon, David J., Robb, Lorraine
Publicado em 2006

Hematopoietic AMPK β1 reduces mouse adipose tissue macrophage inflammation and insulin resistance in obesity

Por Galic, Sandra, Fullerton, Morgan D., Schertzer, Jonathan D., Sikkema, Sarah, Marcinko, Katarina, Walkley, Carl R., Izon, David, Honeyman, Jane, Chen, Zhi-Ping, van Denderen, Bryce J., Kemp, Bruce E., Steinberg, Gregory R.
Publicado em 2011

Anti-apoptotic Mcl-1 is essential for the development and sustained growth of acute myeloid leukemia

Por Glaser, Stefan P., Lee, Erinna F., Trounson, Evelyn, Bouillet, Philippe, Wei, Andrew, Fairlie, W. Douglas, Izon, David J., Zuber, Johannes, Rappaport, Amy R., Herold, Marco J., Alexander, Warren S., Lowe, Scott W., Robb, Lorraine, Strasser, Andreas
Publicado em 2012

Asymmetric cell division during T cell development controls downstream fate

Por Pham, Kim, Shimoni, Raz, Charnley, Mirren, Ludford-Menting, Mandy J., Hawkins, Edwin D., Ramsbottom, Kelly, Oliaro, Jane, Izon, David, Ting, Stephen B., Reynolds, Joseph, Lythe, Grant, Molina-Paris, Carmen, Melichar, Heather, Robey, Ellen, Humbert, Patrick O., Gu, Min, Russell, Sarah M.
Publicado no J Cell Biol (2015)

Asymmetric Cell Division of T Cells Upon Antigen Presentation Utilizes Multiple Conserved Mechanisms

Por Oliaro, Jane, Van Ham, Vanessa, Sacirbegovic, Faruk, Pasam, Anupama, Bomzon, Ze’ev, Pham, Kim, Ludford-Menting, Mandy J., Waterhouse, Nigel J., Bots, Michael, Hawkins, Edwin D., Watt, Sally V., Cluse, Leonie A., Clarke, Chris J.P., Izon, David J., Chang, John T., Thompson, Natalie, Gu, Min, Johnstone, Ricky W., Smyth, Mark J., Humbert, Patrick O., Reiner, Steven L., Russell, Sarah M.
Publicado em 2010