Complete Diabetes Protection Despite Delayed Thymic Tolerance in NOD8.3 TCR Transgenic Mice Due to Antigen-Induced Extrathymic Deletion of T Cells

Prevention of autoimmunity requires the elimination of self-reactive T cells during their development in the thymus and maturation in the periphery. Transgenic NOD mice that overexpress islet-specific glucose 6 phosphatase catalytic subunit–related protein (IGRP) in antigen-presenting cells (NOD-IGR...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Krishnamurthy, Balasubramanian, Chee, Jonathan, Jhala, Gaurang, Fynch, Stacey, Graham, Kate L., Santamaria, Pere, Morahan, Grant, Allison, Janette, Izon, David, Thomas, Helen E., Kay, Thomas W.H.
Format: Artigo
Sprog:Inglês
Udgivet: American Diabetes Association 2012
Fag:
Immunology and Transplantation
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3266425/
https://ncbi.nlm.nih.gov/pubmed/22190647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db11-0948
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker