Asymmetric cell division during T cell development controls downstream fate

During mammalian T cell development, the requirement for expansion of many individual T cell clones, rather than merely expansion of the entire T cell population, suggests a possible role for asymmetric cell division (ACD). We show that ACD of developing T cells controls cell fate through differenti...

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Vydáno v:J Cell Biol
Hlavní autoři: Pham, Kim, Shimoni, Raz, Charnley, Mirren, Ludford-Menting, Mandy J., Hawkins, Edwin D., Ramsbottom, Kelly, Oliaro, Jane, Izon, David, Ting, Stephen B., Reynolds, Joseph, Lythe, Grant, Molina-Paris, Carmen, Melichar, Heather, Robey, Ellen, Humbert, Patrick O., Gu, Min, Russell, Sarah M.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2015
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4576854/
https://ncbi.nlm.nih.gov/pubmed/26370500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201502053
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