Antagonistic effect of CCAAT enhancer-binding protein-α and Pax5 in myeloid or lymphoid lineage choice in common lymphoid progenitors

Lymphoid lineage-committed progenitors, such as common lymphoid progenitors (CLPs), maintain a latent myeloid differentiation potential, which can be initiated by stimulation through exogenously expressed cytokine receptors, including IL-2 receptors. Here we show that the transcription factor CCAAT...

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Main Authors: Hsu, Chia-Lin, King-Fleischman, Angela G., Lai, Anne Y., Matsumoto, Yukie, Weissman, Irving L., Kondo, Motonari
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2006
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1334685/
https://ncbi.nlm.nih.gov/pubmed/16407117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0510304103
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