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Pertussis toxin–sensitive G proteins regulate lymphoid lineage specification in multipotent hematopoietic progenitors

Lymphoid and myeloid lineage segregation is a major developmental step during early hematopoiesis from hematopoietic stem cells. It is not clear, however, whether multipotent progenitors (MPPs) adopt a lymphoid or myeloid fate through stochastic mechanisms, or whether this process can be regulated b...

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Detalhes bibliográficos
Main Authors: Lai, Anne Y., Watanabe, Akiko, O'Brien, Tommy, Kondo, Motonari
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2700316/
https://ncbi.nlm.nih.gov/pubmed/19363218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-01-201939
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