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Developmental Separation of V(D)J Recombinase Expression and Initiation of IgH Recombination in B Lineage Progenitors In Vivo

In B lineage progenitors, V(D)J recombination occurs only during distinct stages of development and is restricted to immunoglobulin loci. This process is thought to be controlled by both regulated expression of the V(D)J recombinase and by limited accessibility of target loci to the recombinase comp...

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Bibliografski detalji
Glavni autori: Borghesi, Lisa, Gerstein, Rachel M.
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2004
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2211822/
https://ncbi.nlm.nih.gov/pubmed/14769853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20031802
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