PU.1 Is Required for the Developmental Progression of Multipotent Progenitors to Common Lymphoid Progenitors

The transcription factor PU.1 is required for the development of mature myeloid and lymphoid cells. Due to this essential role and the importance of PU.1 in regulating several signature markers of lymphoid progenitors, its precise function in early lymphopoiesis has been difficult to define. Here, w...

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Publicat a:Front Immunol
Autors principals: Pang, Swee Heng Milon, de Graaf, Carolyn A., Hilton, Douglas J., Huntington, Nicholas D., Carotta, Sebastian, Wu, Li, Nutt, Stephen L.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2018
Matèries:
Immunology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6005176/
https://ncbi.nlm.nih.gov/pubmed/29942304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.01264
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