PU.1 Is Required for the Developmental Progression of Multipotent Progenitors to Common Lymphoid Progenitors

The transcription factor PU.1 is required for the development of mature myeloid and lymphoid cells. Due to this essential role and the importance of PU.1 in regulating several signature markers of lymphoid progenitors, its precise function in early lymphopoiesis has been difficult to define. Here, w...

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Опубликовано в: :Front Immunol
Главные авторы: Pang, Swee Heng Milon, de Graaf, Carolyn A., Hilton, Douglas J., Huntington, Nicholas D., Carotta, Sebastian, Wu, Li, Nutt, Stephen L.
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2018
Предметы:
Immunology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6005176/
https://ncbi.nlm.nih.gov/pubmed/29942304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.01264
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