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Hematopoietic stem cell expansion and common lymphoid progenitor depletion requires hematopoietic-derived, cell-autonomous TLR4 in a model of chronic endotoxin
Hematopoietic stem and progenitors cells (HSPCs) are activated through toll-like receptor 4 (TLR4) in vitro. However, it remains unclear whether in vivo TLR4 sensing by HSPCs occurs directly or via other cell intermediates. Here, we examine the cellular mechanisms underlying murine hematopoietic ste...
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| Publicado no: | J Immunol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4561199/ https://ncbi.nlm.nih.gov/pubmed/26276875 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1501231 |
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