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Generation of hematopoietic progenitor cell lines with myeloid and lymphoid potential

Investigation of immune cell differentiation and function is limited by shortcomings of suitable and scalable experimental systems. Here we show that an estrogen–regulated form of HOXB8 that is retrovirally delivered into mouse bone marrow cells can be used along with FLT3 ligand to conditionally im...

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Detalhes bibliográficos
Main Authors: Redecke, Vanessa, Wu, Ruiqiong, Zhou, Jingran, Finkelstein, David, Chaturvedi, Vandana, High, Anthony A., Häcker, Hans
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4131762/
https://ncbi.nlm.nih.gov/pubmed/23749299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.2510
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