Fak Depletion in Both Hematopoietic and Non-hematopoietic Niche cells Leads to Hematopoietic Stem Cell Expansion

Hematopoietic stem cells (HSCs) reside in complex bone marrow (BM) microenvironments where niche-induced signals regulate hematopoiesis. Focal adhesion kinase (Fak) is a non-receptor protein tyrosine kinase, which plays an essential role in many cell types, where its activation controls adhesion, mo...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Lu, Jiayun, Sun, Yan, Nombela-Arrieta, Cesar, Du, Karrie P., Park, Shin-Young, Chai, Li, Walkley, Carl, Luo, Hongbo R., Silberstein, Leslie E.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2011
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3307834/
https://ncbi.nlm.nih.gov/pubmed/22155722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2011.11.010
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