Loading...
E47 is required for V(D)J recombinase activity in common lymphoid progenitors
Common lymphoid progenitors (CLPs) are the first bone marrow precursors in which V(D)J recombinase activity is up-regulated. Here, we show that loss of the transcription factor E47 produces a reduced CLP population that lacks V(D)J recombinase activity and D-J(H) rearrangements in vivo. Apart from a...
Saved in:
| Main Authors: | , , , , , |
|---|---|
| Format: | Artigo |
| Language: | Inglês |
| Published: |
The Rockefeller University Press
2005
|
| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2212960/ https://ncbi.nlm.nih.gov/pubmed/16365147 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20051190 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|