Llwytho...

Very Low Affinity B Cells Form Germinal Centers, Become Memory B Cells, and Participate in Secondary Immune Responses When Higher Affinity Competition Is Reduced

To understand the relationship between the affinity of the B cell antigen receptor (BCR) and the immune response to antigen, two lines of immunoglobulin H chain transgenic (Tg) mice were created. H50Gμ(a) and T1(V23)μ(a) mice express μ H chain transgenes that associate with the λ1 L chains to bind t...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Dal Porto, Joseph M., Haberman, Ann M., Kelsoe, Garnett, Shlomchik, Mark J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The Rockefeller University Press 2002
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193705/
https://ncbi.nlm.nih.gov/pubmed/11994427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20011550
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