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High affinity germinal center B cells are actively selected into the plasma cell compartment

A hallmark of T cell–dependent immune responses is the progressive increase in the ability of serum antibodies to bind antigen and provide immune protection. Affinity maturation of the antibody response is thought to be connected with the preferential survival of germinal centre (GC) B cells that ha...

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Detalhes bibliográficos
Main Authors: Phan, Tri Giang, Paus, Didrik, Chan, Tyani D., Turner, Marian L., Nutt, Stephen L., Basten, Antony, Brink, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2118125/
https://ncbi.nlm.nih.gov/pubmed/17030950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20061254
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