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Differentiation of germinal center B cells into plasma cells is initiated by high-affinity antigen and completed by Tfh cells
Plasma cells (PCs) derived from germinal centers (GCs) secrete the high-affinity antibodies required for long-term serological immunity. Nevertheless, the process whereby GC B cells differentiate into PCs is uncharacterized, and the mechanism underlying the selective PC differentiation of only high-...
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| Publicat a: | J Exp Med |
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| Autors principals: | , , , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The Rockefeller University Press
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5413338/ https://ncbi.nlm.nih.gov/pubmed/28363897 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20161533 |
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