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Differentiation of germinal center B cells into plasma cells is initiated by high-affinity antigen and completed by Tfh cells
Plasma cells (PCs) derived from germinal centers (GCs) secrete the high-affinity antibodies required for long-term serological immunity. Nevertheless, the process whereby GC B cells differentiate into PCs is uncharacterized, and the mechanism underlying the selective PC differentiation of only high-...
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| Yayımlandı: | J Exp Med |
|---|---|
| Asıl Yazarlar: | , , , , , , , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
The Rockefeller University Press
2017
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5413338/ https://ncbi.nlm.nih.gov/pubmed/28363897 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20161533 |
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