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Taking Advantage: High Affinity B cells in the Germinal Center Have Lower Death Rates, But Similar Rates of Division Compared to Low Affinity Cells()

B lymphocytes producing high affinity antibodies (Abs) are critical for protection from extracellular pathogens, such as bacteria and parasites. The process by which high affinity B cells are selected during the immune response has never been elucidated. Though it has been shown that high affinity c...

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Autors principals: Anderson, Shannon M., Khalil, Ashraf, Uduman, Mohamed, Hershberg, Uri, Louzoun, Yoram, Haberman, Ann M., Kleinstein, Steven H., Shlomchik, Mark J.
Format: Artigo
Idioma:Inglês
Publicat: 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4106706/
https://ncbi.nlm.nih.gov/pubmed/19917681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0902452
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