Activated germinal center B cells undergo directed migration

Affinity maturation, the fundamental basis for adaptive immunity, is accomplished through somatic hypermutation of B-cell receptors followed by the expansion of rare mutants with higher affinity for the immunizing antigen. This process occurs over a period of weeks in unique microanatomic sites know...

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Bibliographic Details
Published in:Int J Data Min Bioinform
Main Authors: O’Connor, Mark J., Hauser, Anja E., Haberman, Ann M., Kleinstein, Steven H.
Format: Artigo
Language:Inglês
Published: 2011
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4343311/
https://ncbi.nlm.nih.gov/pubmed/21805826
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