Automethylation of G9a and its implication in wider substrate specificity and HP1 binding

Methylation of lysine residues on histones participates in transcriptional gene regulation. Lysine 9 methylation of histone H3 is a transcriptional repression signal, mediated by a family of SET domain containing AdoMet-dependent enzymes. G9a methyltransferase is a euchromatic histone H3 lysine 9 me...

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Hlavní autoři: Chin, Hang Gyeong, Estève, Pierre-Olivier, Pradhan, Mihika, Benner, Jack, Patnaik, Debasis, Carey, Michael F., Pradhan, Sriharsa
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2007
Témata:
Nucleic Acid Enzymes
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2175347/
https://ncbi.nlm.nih.gov/pubmed/17962312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm726
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