טוען...
Insulin stimulates the cleavage and release of the extracellular domain of Klotho by ADAM10 and ADAM17
Cleavage and release (shedding) of membrane proteins is a critical regulatory step in many normal and pathological processes. Evidence suggests that the antiaging transmembrane protein Klotho (KL) is shed from the cell surface by proteolytic cleavage. In this study, we attempted to identify the enzy...
שמור ב:
| Main Authors: | , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
National Academy of Sciences
2007
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2148378/ https://ncbi.nlm.nih.gov/pubmed/18056631 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0709805104 |
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