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Identification of Cleavage Sites Leading to the Shed Form of the Anti-Aging Protein Klotho
[Image: see text] Membrane protein shedding is a critical step in many normal and pathological processes. The anti-aging protein klotho (KL), mainly expressed in kidney and brain, is secreted into the serum and CSF, respectively. KL is proteolytically released, or shed, from the cell surface by ADAM...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American
Chemical Society
2014
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4151695/ https://ncbi.nlm.nih.gov/pubmed/25110992 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi500409n |
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