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The Neuroprotective Effect of Klotho is Mediated via Regulation of Members of the Redox System

Generation of reactive oxygen species (ROS), leading to oxidative damage and neuronal cell death, plays an important role in the pathogenesis of neurodegenerative disorders, including Alzheimer disease. The present study aimed to examine the mechanism by which the anti-aging protein Klotho exerts ne...

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Detalhes bibliográficos
Main Authors: Zeldich, Ella, Chen, Ci-Di, Colvin, Teresa A., Bove-Fenderson, Erin A., Liang, Jennifer, Tucker Zhou, Tracey B., Harris, David A., Abraham, Carmela R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4148892/
https://ncbi.nlm.nih.gov/pubmed/25037225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.567321
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