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A method to specifically activate the Klotho promoter by using zinc finger proteins constructed from modular building blocks and from naturally engineered Egr1 transcription factor backbone
There is an unmet need for treatments for diseases associated with aging. The anti-aging, life-extending and cognition-enhancing protein Klotho is neuroprotective due to its anti-inflammatory, anti-oxidative and pro-myelinating effects. In addition, Klotho is also a tumor suppressor and has benefici...
Tallennettuna:
| Julkaisussa: | FASEB J |
|---|---|
| Päätekijät: | , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2020
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7302970/ https://ncbi.nlm.nih.gov/pubmed/32347987 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.202000171R |
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