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The Neuroprotective Effect of Klotho is Mediated via Regulation of Members of the Redox System

Generation of reactive oxygen species (ROS), leading to oxidative damage and neuronal cell death, plays an important role in the pathogenesis of neurodegenerative disorders, including Alzheimer disease. The present study aimed to examine the mechanism by which the anti-aging protein Klotho exerts ne...

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Détails bibliographiques
Auteurs principaux: Zeldich, Ella, Chen, Ci-Di, Colvin, Teresa A., Bove-Fenderson, Erin A., Liang, Jennifer, Tucker Zhou, Tracey B., Harris, David A., Abraham, Carmela R.
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4148892/
https://ncbi.nlm.nih.gov/pubmed/25037225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.567321
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