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Requirement for T-bet in the aberrant differentiation of unhelped memory CD8(+) T cells
Immunity to intracellular pathogens requires dynamic balance between terminal differentiation of short-lived, cytotoxic effector CD8(+) T cells and self-renewal of central–memory CD8(+) T cells. We now show that T-bet represses transcription of IL-7Rα and drives differentiation of effector and effec...
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| 主要な著者: | , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The Rockefeller University Press
2007
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2118697/ https://ncbi.nlm.nih.gov/pubmed/17698591 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20070841 |
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