Requirement for T-bet in the aberrant differentiation of unhelped memory CD8(+) T cells

Immunity to intracellular pathogens requires dynamic balance between terminal differentiation of short-lived, cytotoxic effector CD8(+) T cells and self-renewal of central–memory CD8(+) T cells. We now show that T-bet represses transcription of IL-7Rα and drives differentiation of effector and effec...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Intlekofer, Andrew M., Takemoto, Naofumi, Kao, Charlly, Banerjee, Arnob, Schambach, Felix, Northrop, John K., Shen, Hao, Wherry, E. John, Reiner, Steven L.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The Rockefeller University Press 2007
Gaiak:
Brief Definitive Reports
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2118697/
https://ncbi.nlm.nih.gov/pubmed/17698591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20070841
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak