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Reduced receptor editing in lupus-prone MRL/lpr mice

The initial B cell repertoire contains a considerable proportion of autoreactive specificities. The first major B cell tolerance checkpoint is at the stage of the immature B cell, where receptor editing is the primary mode of eliminating self-reactivity. The cells that emigrate from the bone marrow...

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Bibliografski detalji
Glavni autori: Lamoureux, Jennifer L., Watson, Lisa C., Cherrier, Marie, Skog, Patrick, Nemazee, David, Feeney, Ann J.
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2007
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2118512/
https://ncbi.nlm.nih.gov/pubmed/17967905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20071268
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