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Proliferative arrest and rapid turnover of thymic epithelial cells expressing Aire

Expression of autoimmune regulator (Aire) by thymic medullary epithelial cells (MECs) is critical for central tolerance of self. To explore the mechanism by which such a rare cell population imposes tolerance on the large repertoire of differentiating thymocytes, we examined the proliferation and tu...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Gray, Daniel, Abramson, Jakub, Benoist, Christophe, Mathis, Diane
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The Rockefeller University Press 2007
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2118482/
https://ncbi.nlm.nih.gov/pubmed/17908938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20070795
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