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Proliferative arrest and rapid turnover of thymic epithelial cells expressing Aire
Expression of autoimmune regulator (Aire) by thymic medullary epithelial cells (MECs) is critical for central tolerance of self. To explore the mechanism by which such a rare cell population imposes tolerance on the large repertoire of differentiating thymocytes, we examined the proliferation and tu...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
The Rockefeller University Press
2007
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2118482/ https://ncbi.nlm.nih.gov/pubmed/17908938 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20070795 |
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