Neonatal tolerance revisited: a perinatal window for Aire control of autoimmunity

There has long been conceptual and experimental support for, but also challenges to, the notion that the initial period of the immune system's development is particularly important for the establishment of tolerance to self. The display of self-antigens by thymic epithelial cells is key to indu...

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Bibliographic Details
Main Authors: Guerau-de-Arellano, Mireia, Martinic, Marianne, Benoist, Christophe, Mathis, Diane
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2009
Subjects:
Brief Definitive Report
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2715060/
https://ncbi.nlm.nih.gov/pubmed/19487417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20090300
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