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Neonatal tolerance revisited: a perinatal window for Aire control of autoimmunity

There has long been conceptual and experimental support for, but also challenges to, the notion that the initial period of the immune system's development is particularly important for the establishment of tolerance to self. The display of self-antigens by thymic epithelial cells is key to indu...

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Autori principali: Guerau-de-Arellano, Mireia, Martinic, Marianne, Benoist, Christophe, Mathis, Diane
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2715060/
https://ncbi.nlm.nih.gov/pubmed/19487417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20090300
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