Cytotoxic T Lymphocyte–associated Antigen 4 (CTLA-4) Regulates the Unfolding of Autoimmune Diabetes

Evidence has been accumulating that shows that insulin-dependent diabetes is subject to immunoregulation. To determine whether cytotoxic T lymphocyte–associated antigen 4 (CTLA-4) is involved, we injected anti–CTLA-4 mAb into a TCR transgenic model of diabetes at different stages of disease. When in...

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Hlavní autoři: Lühder, Fred, Höglund, Petter, Allison, James P., Benoist, Christophe, Mathis, Diane
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 1998
Témata:
Brief Definitive Report
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2212113/
https://ncbi.nlm.nih.gov/pubmed/9449722
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