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Danger-free autoimmune disease in Aire-deficient mice

The danger theory of immune tolerance asserts that environmental factors hold primacy over lymphocyte autoreactivity in initiating autoimmune disease. We sought to test this contention using the Aire-deficient mouse model of the human disease, autoimmune polyendocrinopathy–candidiasis–ectodermal dys...

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Bibliografische gegevens
Hoofdauteurs: Gray, Daniel H. D., Gavanescu, Irina, Benoist, Christophe, Mathis, Diane
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2007
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2084319/
https://ncbi.nlm.nih.gov/pubmed/17991771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0709160104
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