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Prostacyclin-IP signaling and prostaglandin E(2)-EP2/EP4 signaling both mediate joint inflammation in mouse collagen-induced arthritis

Prostaglandin (PG)I(2) (prostacyclin [PGI]) and PGE(2) are abundantly present in the synovial fluid of rheumatoid arthritis (RA) patients. Although the role of PGE(2) in RA has been well studied, how much PGI(2) contributes to RA is little known. To examine this issue, we backcrossed mice lacking th...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Honda, Tetsuya, Segi-Nishida, Eri, Miyachi, Yoshiki, Narumiya, Shuh
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The Rockefeller University Press 2006
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2118213/
https://ncbi.nlm.nih.gov/pubmed/16446378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20051310
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