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Prostacyclin-IP signaling and prostaglandin E(2)-EP2/EP4 signaling both mediate joint inflammation in mouse collagen-induced arthritis
Prostaglandin (PG)I(2) (prostacyclin [PGI]) and PGE(2) are abundantly present in the synovial fluid of rheumatoid arthritis (RA) patients. Although the role of PGE(2) in RA has been well studied, how much PGI(2) contributes to RA is little known. To examine this issue, we backcrossed mice lacking th...
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| 主要な著者: | , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The Rockefeller University Press
2006
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2118213/ https://ncbi.nlm.nih.gov/pubmed/16446378 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20051310 |
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